Bioinformatics And Biosensors — Part 1 MCQs with Explanations
Practice high-yield Biotechnology Engineering MCQs on Bioinformatics And Biosensors — Part 1 with worked academic solutions for PPSC, FPSC, NIH, NTS.
Questions
40
Difficulty Level
Exam-Level
Target Exams
PPSC, FPSC, NIH...
Estimated Time
48 mins
Exam-Level PPSC FPSC NIH NTS
Verified for Commission Syllabus • Oct 14, 2026
40
Verified Practice Questions
Interactive test mode with detailed academic worked solutions
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🎉 Set complete! All 40 questions answered.
Question 1 of 40
★ PPSC
★ FPSC
★ PPSC
★ FPSC
Microarray gene chips will eventually be used to
Correct Answer: Option D — Both A and B
Detailed Academic Explanation:
Both A and B is the correct answer to “Microarray gene chips will eventually be used to”. This question is standard in competitive examination syllabi for Bioinformatics And Biosensors.
💡Key Conceptual Anchor:Bioinformatics And Biosensors
Question 2 of 40
★ PPSC
★ FPSC
★ PPSC
★ FPSC
Which of the following is least likely to be involved in stabilizing the three dimensional folding of most proteins?
Correct Answer: Option D — Ester bonds
Detailed Academic Explanation:
Ester bonds is the correct answer to “Which of the following is least likely to be involved in stabilizing the three dimensional folding of most proteins”. This question is standard in competitive examination syllabi for Bioinformatics And Biosensors.
💡Key Conceptual Anchor:Bioinformatics And Biosensors
Question 3 of 40
★ PPSC
★ FPSC
★ PPSC
★ FPSC
BLAST is an algorithm for comparing
Correct Answer: Option A — Sequences
Detailed Academic Explanation:
Sequences is the correct answer to “BLAST is an algorithm for comparing”. This question is standard in competitive examination syllabi for Bioinformatics And Biosensors.
💡Key Conceptual Anchor:Bioinformatics And Biosensors
Question 4 of 40
★ PPSC
★ FPSC
★ PPSC
★ FPSC
Characterizing molecular component is
Correct Answer: Option D — Bioinformatics
Detailed Academic Explanation:
Bioinformatics is the correct answer to “Characterizing molecular component is”. This question is standard in competitive examination syllabi for Bioinformatics And Biosensors.
💡Key Conceptual Anchor:Bioinformatics And Biosensors
Question 5 of 40
★ PPSC
★ FPSC
★ PPSC
★ FPSC
Lux AB bioreporter contain
Correct Answer: Option D — Lux A & Lux B genes
Detailed Academic Explanation:
Lux A & Lux B genes is the correct answer to “Lux AB bioreporter contain”. This question is standard in competitive examination syllabi for Bioinformatics And Biosensors.
💡Key Conceptual Anchor:Bioinformatics And Biosensors
Question 6 of 40
★ PPSC
★ FPSC
★ PPSC
★ FPSC
Sometimes signal only occurs when a secondary substrate like the following is added to the bioassay
Correct Answer: Option D — Both A and B
Detailed Academic Explanation:
Both A and B is the correct answer to “Sometimes signal only occurs when a secondary substrate like the following is added to the bioassay”. This question is standard in competitive examination syllabi for Bioinformatics And Biosensors.
💡Key Conceptual Anchor:Bioinformatics And Biosensors
Question 7 of 40
★ PPSC
★ FPSC
★ PPSC
★ FPSC
Which of the following can detect extremely low levels of proteins, hormones, pollutants, gases and other molecules?
Correct Answer: Option C — Biosensor
Detailed Academic Explanation:
Biosensor is the correct answer to “Which of the following can detect extremely low levels of proteins, hormones, pollutants, gases and other molecules”. This question is standard in competitive examination syllabi for Bioinformatics And Biosensors.
💡Key Conceptual Anchor:Bioinformatics And Biosensors
Question 8 of 40
★ PPSC
★ FPSC
★ PPSC
★ FPSC
The field that is concerned with the management and analysis of biological data using computers
Correct Answer: Option C — Bioinformatics
Detailed Academic Explanation:
Bioinformatics is the correct answer to “The field that is concerned with the management and analysis of biological data using computers”. This question is standard in competitive examination syllabi for Bioinformatics And Biosensors.
💡Key Conceptual Anchor:Bioinformatics And Biosensors
Question 9 of 40
★ PPSC
★ FPSC
★ PPSC
★ FPSC
Several major international databases for application to genomics and proteomics have been established as mirror site under the
Correct Answer: Option B — NJVM
Detailed Academic Explanation:
NJVM is the correct answer to “Several major international databases for application to genomics and proteomics have been established as mirror site under the”. This question is standard in competitive examination syllabi for Bioinformatics And Biosensors.
💡Key Conceptual Anchor:Bioinformatics And Biosensors
Question 10 of 40
★ PPSC
★ FPSC
★ PPSC
★ FPSC
ESTs are
Correct Answer: Option C — mRNA
Detailed Academic Explanation:
Option "mRNA" is the correct answer for this question under Bioinformatics And Biosensors.
💡Key Conceptual Anchor:Bioinformatics And Biosensors
Question 11 of 40
★ PPSC
★ FPSC
★ PPSC
★ FPSC
The translated genes of genomes that encode proteins are referred to as
Correct Answer: Option A — The open reading frame
Detailed Academic Explanation:
The open reading frame is the correct answer to “The translated genes of genomes that encode proteins are referred to as”. This question is standard in competitive examination syllabi for Bioinformatics And Biosensors.
💡Key Conceptual Anchor:Bioinformatics And Biosensors
Question 12 of 40
★ PPSC
★ FPSC
★ PPSC
★ FPSC
Who first developed the DNA sequencing approach using dideoxynucleoside in DNA synthesis?
Correct Answer: Option C — Sanger
Detailed Academic Explanation:
Sanger is the correct answer to “Who first developed the DNA sequencing approach using dideoxynucleoside in DNA synthesis”. This question is standard in competitive examination syllabi for Bioinformatics And Biosensors.
💡Key Conceptual Anchor:Bioinformatics And Biosensors
Question 13 of 40
★ PPSC
★ FPSC
★ PPSC
★ FPSC
Labelling a stretch of DNA according to its function is called
Correct Answer: Option C — Annotation
Detailed Academic Explanation:
Annotation is the correct answer to “Labelling a stretch of DNA according to its function is called”. This question is standard in competitive examination syllabi for Bioinformatics And Biosensors.
💡Key Conceptual Anchor:Bioinformatics And Biosensors
Question 14 of 40
★ PPSC
★ FPSC
★ PPSC
★ FPSC
Which of the following is mismatched
Correct Answer: Option D — None of the above
Detailed Academic Explanation:
None of the above is the correct answer to “Which of the following is mismatched”. This question is standard in competitive examination syllabi for Bioinformatics And Biosensors.
💡Key Conceptual Anchor:Bioinformatics And Biosensors
Question 15 of 40
★ PPSC
★ FPSC
★ PPSC
★ FPSC
To best understand the function of a gene; analysis is often most useful at
Correct Answer: Option C — Protein level
Detailed Academic Explanation:
Protein level is the correct answer to “To best understand the function of a gene; analysis is often most useful at”. This question is standard in competitive examination syllabi for Bioinformatics And Biosensors.
💡Key Conceptual Anchor:Bioinformatics And Biosensors
Question 16 of 40
★ PPSC
★ FPSC
★ PPSC
★ FPSC
Which is wrong?
Correct Answer: Option D — None of these
Detailed Academic Explanation:
None of these is the correct answer to “Which is wrong”. This question is standard in competitive examination syllabi for Bioinformatics And Biosensors.
💡Key Conceptual Anchor:Bioinformatics And Biosensors
Question 17 of 40
★ PPSC
★ FPSC
★ PPSC
★ FPSC
The first bioinformatics database was created by
Correct Answer: Option B — Dayhoff
Detailed Academic Explanation:
Dayhoff is the correct answer to “The first bioinformatics database was created by”. This question is standard in competitive examination syllabi for Bioinformatics And Biosensors.
💡Key Conceptual Anchor:Bioinformatics And Biosensors
Question 18 of 40
★ PPSC
★ FPSC
★ PPSC
★ FPSC
Which of the following is a limitation of blotting technique
Correct Answer: Option C — Both A and B
Detailed Academic Explanation:
Both A and B is the correct answer to “Which of the following is a limitation of blotting technique”. This question is standard in competitive examination syllabi for Bioinformatics And Biosensors.
💡Key Conceptual Anchor:Bioinformatics And Biosensors
Question 19 of 40
★ PPSC
★ FPSC
★ PPSC
★ FPSC
Eukaryotic DNA
Correct Answer: Option B — Takes part indirectly in protein synthesis, the DNA itself stays in the nucleus
Detailed Academic Explanation:
Takes part indirectly in protein synthesis, the DNA itself stays in the nucleus is the correct answer to “Eukaryotic DNA”. This question is standard in competitive examination syllabi for Bioinformatics And Biosensors.
💡Key Conceptual Anchor:Bioinformatics And Biosensors
Question 20 of 40
★ PPSC
★ FPSC
★ PPSC
★ FPSC
What step of DNA sequencing is skipped during shot-gun sequencing?
Correct Answer: Option D — Mapping step
Detailed Academic Explanation:
Mapping step is the correct answer to “What step of DNA sequencing is skipped during shot-gun sequencing”. This question is standard in competitive examination syllabi for Bioinformatics And Biosensors.
💡Key Conceptual Anchor:Bioinformatics And Biosensors
Question 21 of 40
★ PPSC
★ FPSC
★ PPSC
★ FPSC
Reporter gene is turned on when
Correct Answer: Option A — Promoter gene is turned on
Detailed Academic Explanation:
Promoter gene is turned on is the correct answer to “Reporter gene is turned on when”. This question is standard in competitive examination syllabi for Bioinformatics And Biosensors.
💡Key Conceptual Anchor:Bioinformatics And Biosensors
Question 22 of 40
★ PPSC
★ FPSC
★ PPSC
★ FPSC
Which of the following method makes use of information that can be expressed through intra and intermolecular distances
Correct Answer: Option B — Distance geometry (DG)
Detailed Academic Explanation:
Distance geometry (DG) is the correct answer to “Which of the following method makes use of information that can be expressed through intra and intermolecular distances”. This question is standard in competitive examination syllabi for Bioinformatics And Biosensors.
💡Key Conceptual Anchor:Bioinformatics And Biosensors
Question 23 of 40
★ PPSC
★ FPSC
★ PPSC
★ FPSC
The goal of . . . . . . . . is to determine the location of specific genes within the genome.
Correct Answer: Option D — Mapping
Detailed Academic Explanation:
Mapping is the correct answer to “The goal of . . . . . . . . is to determine the location of specific genes within the genome.”. This question is standard in competitive examination syllabi for Bioinformatics And Biosensors.
💡Key Conceptual Anchor:Bioinformatics And Biosensors
Question 24 of 40
★ PPSC
★ FPSC
★ PPSC
★ FPSC
Today; computer program such as . . . . . . . . are used daily to search sequences form more than 260,000 organism containing over . . . . . . . . billion nucleotides
Correct Answer: Option B — BLAST, 190
Detailed Academic Explanation:
BLAST, 190 is the correct answer to “Today; computer program such as . . . . . . . . are used daily to search sequences form more than 260,000 organism containing over . . . . . . . . billion nucleotides”. This question is standard in competitive examination syllabi for Bioinformatics And Biosensors.
💡Key Conceptual Anchor:Bioinformatics And Biosensors
Question 25 of 40
★ PPSC
★ FPSC
★ PPSC
★ FPSC
Which of the following is used to read light signal
Correct Answer: Option C — Both A and B
Detailed Academic Explanation:
Both A and B is the correct answer to “Which of the following is used to read light signal”. This question is standard in competitive examination syllabi for Bioinformatics And Biosensors.
💡Key Conceptual Anchor:Bioinformatics And Biosensors
Question 26 of 40
★ PPSC
★ FPSC
★ PPSC
★ FPSC
Which among the following is likely to be important for structure based drug design?
Correct Answer: Option B — 2D-QSAR
Detailed Academic Explanation:
2D-QSAR is the correct answer to “Which among the following is likely to be important for structure based drug design”. This question is standard in competitive examination syllabi for Bioinformatics And Biosensors.
💡Key Conceptual Anchor:Bioinformatics And Biosensors
Question 27 of 40
★ PPSC
★ FPSC
★ PPSC
★ FPSC
Bioreporters refer to
Correct Answer: Option C — Intact, living microbial cells-genetically engineered
Detailed Academic Explanation:
Intact, living microbial cells-genetically engineered is the correct answer to “Bioreporters refer to”. This question is standard in competitive examination syllabi for Bioinformatics And Biosensors.
💡Key Conceptual Anchor:Bioinformatics And Biosensors
Question 28 of 40
★ PPSC
★ FPSC
★ PPSC
★ FPSC
Which type of genomics studies the physical nature of genomes?
Correct Answer: Option B — Structural genomics
Detailed Academic Explanation:
Structural genomics is the correct answer to “Which type of genomics studies the physical nature of genomes”. This question is standard in competitive examination syllabi for Bioinformatics And Biosensors.
💡Key Conceptual Anchor:Bioinformatics And Biosensors
Question 29 of 40
★ PPSC
★ FPSC
★ PPSC
★ FPSC
Which among the following is a compiled programming language?
Correct Answer: Option A — PERL
Detailed Academic Explanation:
PERL is the correct answer to “Which among the following is a compiled programming language”. This question is standard in competitive examination syllabi for Bioinformatics And Biosensors.
💡Key Conceptual Anchor:Bioinformatics And Biosensors
Question 30 of 40
★ PPSC
★ FPSC
★ PPSC
★ FPSC
Luciferases can be found in bacteria, algae, fungi, jellyfish, insects, shrimp and squid and the resulting light that these organisms produce is termed
Correct Answer: Option B — Bioluminescence
Detailed Academic Explanation:
Bioluminescence is the correct answer to “Luciferases can be found in bacteria, algae, fungi, jellyfish, insects, shrimp and squid and the resulting light that these organisms produce is termed”. This question is standard in competitive examination syllabi for Bioinformatics And Biosensors.
💡Key Conceptual Anchor:Bioinformatics And Biosensors
Question 31 of 40
★ PPSC
★ FPSC
★ PPSC
★ FPSC
Match the following and select the correct answer: Column-I Column-II a. UPGMA 1. Protein sequence database b. CLUSTAL 2. Phylogenetic analysi c. SWISS-PROT 3. 3-D structure visualization d. Ras Mol 4. Multiple sequence alignment
Correct Answer: Option A — a-2, b-4, c-1, d-3
Detailed Academic Explanation:
a-2, b-4, c-1, d-3 is the correct answer to “Match the following and select the correct answer: Column-I Column-II a. UPGMA 1. Protein sequence database b. CLUSTAL 2. Phylogenetic analysi c. SWISS-PROT 3. 3-D structure visualization d. Ras Mol 4. Multiple sequence alignment”. This question is standard in competitive examination syllabi for Bioinformatics And Biosensors.
💡Key Conceptual Anchor:Bioinformatics And Biosensors
Question 32 of 40
★ PPSC
★ FPSC
★ PPSC
★ FPSC
The genome-wide comparative mRNA expression profile between normal and cancer cells can be studied using the microarray technology. The basic approach of this technology is
Correct Answer: Option C — Hybridization of fluorescently labelled cDNAs from normal and cancer cells to a single glass slide containing immobilized clones of human cDNAs
Detailed Academic Explanation:
Hybridization of fluorescently labelled cDNAs from normal and cancer cells to a single glass slide containing immobilized clones of human cDNAs is the correct answer to “The genome-wide comparative mRNA expression profile between normal and cancer cells can be studied using the microarray technology. The basic approach of this technology is”. This question is standard in competitive examination syllabi for Bioinformatics And Biosensors.
💡Key Conceptual Anchor:Bioinformatics And Biosensors
Question 33 of 40
★ PPSC
★ FPSC
★ PPSC
★ FPSC
Sequence analysis of a human gene NFI showed that a region of the protein has homology to a yeast protein called Ira. Which of the following you think is most appropriate explanation for this sequence homology?
Correct Answer: Option B — Human and yeast are closely related
Detailed Academic Explanation:
Human and yeast are closely related is the correct answer to “Sequence analysis of a human gene NFI showed that a region of the protein has homology to a yeast protein called Ira. Which of the following you think is most appropriate explanation for this sequence homology”. This question is standard in competitive examination syllabi for Bioinformatics And Biosensors.
💡Key Conceptual Anchor:Bioinformatics And Biosensors
Question 34 of 40
★ PPSC
★ FPSC
★ PPSC
★ FPSC
Which of the following is the most preferred website for searching original research articles in medicine?
Correct Answer: Option A — Entrez
Detailed Academic Explanation:
Entrez is the correct answer to “Which of the following is the most preferred website for searching original research articles in medicine”. This question is standard in competitive examination syllabi for Bioinformatics And Biosensors.
💡Key Conceptual Anchor:Bioinformatics And Biosensors
Question 35 of 40
★ PPSC
★ FPSC
★ PPSC
★ FPSC
Which bacterial genome was the first to be completely sequenced?
Correct Answer: Option C — Haemophilus influenzae
Detailed Academic Explanation:
Haemophilus influenzae is the correct answer to “Which bacterial genome was the first to be completely sequenced”. This question is standard in competitive examination syllabi for Bioinformatics And Biosensors.
💡Key Conceptual Anchor:Bioinformatics And Biosensors
Question 36 of 40
★ PPSC
★ FPSC
★ PPSC
★ FPSC
Which of the following gene is most commonly found to have mutated when a cancer is detected and biosensors are used in this
Correct Answer: Option B — P53
Detailed Academic Explanation:
P53 is the correct answer to “Which of the following gene is most commonly found to have mutated when a cancer is detected and biosensors are used in this”. This question is standard in competitive examination syllabi for Bioinformatics And Biosensors.
💡Key Conceptual Anchor:Bioinformatics And Biosensors
Question 37 of 40
★ PPSC
★ FPSC
★ PPSC
★ FPSC
Phylogeny describes a species
Correct Answer: Option C — Evolutionary history
Detailed Academic Explanation:
Evolutionary history is the correct answer to “Phylogeny describes a species”. This question is standard in competitive examination syllabi for Bioinformatics And Biosensors.
💡Key Conceptual Anchor:Bioinformatics And Biosensors
Question 38 of 40
★ PPSC
★ FPSC
★ PPSC
★ FPSC
Firefly luciferase catalyzes a reaction that produces visible light in the
Correct Answer: Option B — 550 - 575 nm range
Detailed Academic Explanation:
550 - 575 nm range is the correct answer to “Firefly luciferase catalyzes a reaction that produces visible light in the”. This question is standard in competitive examination syllabi for Bioinformatics And Biosensors.
💡Key Conceptual Anchor:Bioinformatics And Biosensors
Question 39 of 40
★ PPSC
★ FPSC
★ PPSC
★ FPSC
An example homology and similarity tool
Correct Answer: Option D — BLAST
Detailed Academic Explanation:
BLAST is the correct answer to “An example homology and similarity tool”. This question is standard in competitive examination syllabi for Bioinformatics And Biosensors.
💡Key Conceptual Anchor:Bioinformatics And Biosensors
Question 40 of 40
★ PPSC
★ FPSC
★ PPSC
★ FPSC
Which of the following is a kind of DNA sequences
Correct Answer: Option D — All are correct
Detailed Academic Explanation:
All are correct is the correct answer to “Which of the following is a kind of DNA sequences”. This question is standard in competitive examination syllabi for Bioinformatics And Biosensors.
💡Key Conceptual Anchor:Bioinformatics And Biosensors
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Analytical Tools In Biotechnology — Part 1
Master the next curriculum module with 40 exam-standard MCQs.
💡Examiner's Advisory for Biotechnology Engineering
In competitive commission exams (FPSC, PPSC, KPPSC, SPSC, CSS, PMS), questions are frequently phrased with distractor options designed to catch rote learners. Whenever you answer an MCQ, read the Detailed Academic Explanation and Conceptual Anchor to understand why the remaining options are incorrect.