Cell Biology In Biotechnology — Part 1 MCQs with Explanations
Practice high-yield Biotechnology Engineering MCQs on Cell Biology In Biotechnology — Part 1 with worked academic solutions for PPSC, FPSC, NIH, NTS.
Questions
40
Difficulty Level
Exam-Level
Target Exams
PPSC, FPSC, NIH...
Estimated Time
48 mins
Exam-Level PPSC FPSC NIH NTS
Verified for Commission Syllabus • Oct 14, 2026
40
Verified Practice Questions
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Question 1 of 40
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★ FPSC
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Which one of the following changes occurs in a directionally migrating eukaryotic cell?
Correct Answer: Option C — The nucleus moves towards the back and behind the Golgi
Detailed Academic Explanation:
The nucleus moves towards the back and behind the Golgi is the correct answer to “Which one of the following changes occurs in a directionally migrating eukaryotic cell”. This question is standard in competitive examination syllabi for Cell Biology In Biotechnology.
💡Key Conceptual Anchor:Cell Biology In Biotechnology
Question 2 of 40
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Structured William's model P. Can describe the changes in intracellular components of the cell during growth. Q. Cannot describe the death phase of the cells. R. Can describe the variation of size of cells in the different phases of growth. S. Cannot describe the lag period of growth. Which one of the following is correct?
Correct Answer: Option D — P, R and S only
Detailed Academic Explanation:
P, R and S only is the correct answer to “Structured William's model P. Can describe the changes in intracellular components of the cell during growth. Q. Cannot describe the death phase of the cells. R. Can describe the variation of size of cells in the different phases of growth. S. Cannot describe the lag period of growth. Which one of the following is correct”. This question is standard in competitive examination syllabi for Cell Biology In Biotechnology.
💡Key Conceptual Anchor:Cell Biology In Biotechnology
Question 3 of 40
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Metaplasia represents
Correct Answer: Option B — Transformation of one differentiated cell type to another
Detailed Academic Explanation:
Transformation of one differentiated cell type to another is the correct answer to “Metaplasia represents”. This question is standard in competitive examination syllabi for Cell Biology In Biotechnology.
💡Key Conceptual Anchor:Cell Biology In Biotechnology
Question 4 of 40
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Which one of the following organelles disappears during cell division and is regenerated in the daughter cells?
Correct Answer: Option B — Golgi
Detailed Academic Explanation:
Golgi is the correct answer to “Which one of the following organelles disappears during cell division and is regenerated in the daughter cells”. This question is standard in competitive examination syllabi for Cell Biology In Biotechnology.
💡Key Conceptual Anchor:Cell Biology In Biotechnology
Question 5 of 40
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The process by which intracellular macromolecules are supplied for lysosomal degradation during nutrient starvation is
Correct Answer: Option B — Autophagy
Detailed Academic Explanation:
Autophagy is the correct answer to “The process by which intracellular macromolecules are supplied for lysosomal degradation during nutrient starvation is”. This question is standard in competitive examination syllabi for Cell Biology In Biotechnology.
💡Key Conceptual Anchor:Cell Biology In Biotechnology
Question 6 of 40
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The type of transport that does not reach V max , is
Correct Answer: Option A — Simple diffusion across lipid bilayer
Detailed Academic Explanation:
Simple diffusion across lipid bilayer is the correct answer to “The type of transport that does not reach V max , is”. This question is standard in competitive examination syllabi for Cell Biology In Biotechnology.
💡Key Conceptual Anchor:Cell Biology In Biotechnology
Question 7 of 40
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Neurotransmitter at the neuromuscular junction is
Correct Answer: Option C — Acetylcholine
Detailed Academic Explanation:
Acetylcholine is the correct answer to “Neurotransmitter at the neuromuscular junction is”. This question is standard in competitive examination syllabi for Cell Biology In Biotechnology.
💡Key Conceptual Anchor:Cell Biology In Biotechnology
Question 8 of 40
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Which of the following statements about Na+ - K+ ATPase is correct?
Correct Answer: Option D — It indirectly regulates the volume of the cell
Detailed Academic Explanation:
It indirectly regulates the volume of the cell is the correct answer to “Which of the following statements about Na+ - K+ ATPase is correct”. This question is standard in competitive examination syllabi for Cell Biology In Biotechnology.
💡Key Conceptual Anchor:Cell Biology In Biotechnology
Question 9 of 40
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Ras protein is a
Correct Answer: Option B — Monomeric GTPase involved in relaying signal from cell surface to nucleus
Detailed Academic Explanation:
Monomeric GTPase involved in relaying signal from cell surface to nucleus is the correct answer to “Ras protein is a”. This question is standard in competitive examination syllabi for Cell Biology In Biotechnology.
💡Key Conceptual Anchor:Cell Biology In Biotechnology
Question 10 of 40
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How many mitotic divisions shall occur to produce 64 cells from 2 cells
Correct Answer: Option A — 5
Detailed Academic Explanation:
5 is the correct answer to “How many mitotic divisions shall occur to produce 64 cells from 2 cells”. This question is standard in competitive examination syllabi for Cell Biology In Biotechnology.
💡Key Conceptual Anchor:Cell Biology In Biotechnology
Question 11 of 40
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Which one of the following intermediate filament proteins is present in the nucleus?
Correct Answer: Option B — Lamin
Detailed Academic Explanation:
Lamin is the correct answer to “Which one of the following intermediate filament proteins is present in the nucleus”. This question is standard in competitive examination syllabi for Cell Biology In Biotechnology.
💡Key Conceptual Anchor:Cell Biology In Biotechnology
Question 12 of 40
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Secretory proteins synthesized by ER-associated ribosomes traverse through
Correct Answer: Option C — The Golgi apparatus
Detailed Academic Explanation:
The Golgi apparatus is the correct answer to “Secretory proteins synthesized by ER-associated ribosomes traverse through”. This question is standard in competitive examination syllabi for Cell Biology In Biotechnology.
💡Key Conceptual Anchor:Cell Biology In Biotechnology
Question 13 of 40
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Which one of the following result is expected when a mammalian cell in S-phase is fused with another in G2?
Correct Answer: Option A — G2 phase nucleus will wait for S-phase nucleus to complete the replication and both the nuclei simultaneously enter into M-phase
Detailed Academic Explanation:
G2 phase nucleus will wait for S-phase nucleus to complete the replication and both the nuclei simultaneously enter into M-phase is the correct answer to “Which one of the following result is expected when a mammalian cell in S-phase is fused with another in G2”. This question is standard in competitive examination syllabi for Cell Biology In Biotechnology.
💡Key Conceptual Anchor:Cell Biology In Biotechnology
Question 14 of 40
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If a fluorescent dye is injected into the lumen of the endoplasmic reticulum (ER), in which of the following compartments can fluorescence signal can be observed?
Correct Answer: Option D — ER, Golgi and nuclear envelope
Detailed Academic Explanation:
ER, Golgi and nuclear envelope is the correct answer to “If a fluorescent dye is injected into the lumen of the endoplasmic reticulum (ER), in which of the following compartments can fluorescence signal can be observed”. This question is standard in competitive examination syllabi for Cell Biology In Biotechnology.
💡Key Conceptual Anchor:Cell Biology In Biotechnology
Question 15 of 40
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In a typical mitotic cell division cycle in eukaryotes, M phase occurs immediately after the
Correct Answer: Option D — G2 phase
Detailed Academic Explanation:
G2 phase is the correct answer to “In a typical mitotic cell division cycle in eukaryotes, M phase occurs immediately after the”. This question is standard in competitive examination syllabi for Cell Biology In Biotechnology.
💡Key Conceptual Anchor:Cell Biology In Biotechnology
Question 16 of 40
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In the course of cell cycle, the level of the protein cyclin abruptly falls during
Correct Answer: Option D — M phase
Detailed Academic Explanation:
M phase is the correct answer to “In the course of cell cycle, the level of the protein cyclin abruptly falls during”. This question is standard in competitive examination syllabi for Cell Biology In Biotechnology.
💡Key Conceptual Anchor:Cell Biology In Biotechnology
Question 17 of 40
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Hayflick limit of mammalian cells refers to which one of the following?
Correct Answer: Option A — Cells in primary cell culture undergo senescence after 50-60 passages
Detailed Academic Explanation:
Cells in primary cell culture undergo senescence after 50-60 passages is the correct answer to “Hayflick limit of mammalian cells refers to which one of the following”. This question is standard in competitive examination syllabi for Cell Biology In Biotechnology.
💡Key Conceptual Anchor:Cell Biology In Biotechnology
Question 18 of 40
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A cargo has to be delivered from the centre of the cell to the cell periphery using the microtubule network. To which proteins does it need to be associated with
Correct Answer: Option B — Kinesin
Detailed Academic Explanation:
Kinesin is the correct answer to “A cargo has to be delivered from the centre of the cell to the cell periphery using the microtubule network. To which proteins does it need to be associated with”. This question is standard in competitive examination syllabi for Cell Biology In Biotechnology.
💡Key Conceptual Anchor:Cell Biology In Biotechnology
Question 19 of 40
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Match the items in Group I with Group II . Group I Group II P. Receptor tyrosine kinase 1. Inactivation of G-proteins b. Q. Cyclic GMP (cGMP) 2. Reception of insulin signal R. GTPase activating protein (GAP) 3. Thyroid hormone S. Nuclear receptor 4. Receptor guanylyl cyclase
Correct Answer: Option D — P-2, Q-4, R-1, S-3
Detailed Academic Explanation:
P-2, Q-4, R-1, S-3 is the correct answer to “Match the items in Group I with Group II . Group I Group II P. Receptor tyrosine kinase 1. Inactivation of G-proteins b. Q. Cyclic GMP (cGMP) 2. Reception of insulin signal R. GTPase activating protein (GAP) 3. Thyroid hormone S. Nuclear receptor 4. Receptor guanylyl cyclase”. This question is standard in competitive examination syllabi for Cell Biology In Biotechnology.
💡Key Conceptual Anchor:Cell Biology In Biotechnology
Question 20 of 40
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In a migrating cell the relative position of the . . . . . . . . and the . . . . . . . . determines the polarity of the cell
Correct Answer: Option A — Nucleus, Golgi
Detailed Academic Explanation:
Nucleus, Golgi is the correct answer to “In a migrating cell the relative position of the . . . . . . . . and the . . . . . . . . determines the polarity of the cell”. This question is standard in competitive examination syllabi for Cell Biology In Biotechnology.
💡Key Conceptual Anchor:Cell Biology In Biotechnology
Question 21 of 40
★ PPSC
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★ PPSC
★ FPSC
Which one of the following statement is incorrect about facilitated diffusion?
Correct Answer: Option D — It works against the concentration gradient
Detailed Academic Explanation:
It works against the concentration gradient is the correct answer to “Which one of the following statement is incorrect about facilitated diffusion”. This question is standard in competitive examination syllabi for Cell Biology In Biotechnology.
💡Key Conceptual Anchor:Cell Biology In Biotechnology
Question 22 of 40
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Determine the correctness or otherwise of the following Assertion (A) and the Reason (R) . Assertion: The elucidation of ribosome structure helps in the development of new generation drugs. Reason: The high resolution of macromolecular structure has enabled in structure-based drug design.
Correct Answer: Option A — Both (A) and (R) are true and (R) is the correct reason for (A)
Detailed Academic Explanation:
Both (A) and (R) are true and (R) is the correct reason for (A) is the correct answer to “Determine the correctness or otherwise of the following Assertion (A) and the Reason (R) . Assertion: The elucidation of ribosome structure helps in the development of new generation drugs. Reason: The high resolution of macromolecular structure has enabled in structure-based drug design.”. This question is standard in competitive examination syllabi for Cell Biology In Biotechnology.
💡Key Conceptual Anchor:Cell Biology In Biotechnology
Question 23 of 40
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The transport that will be the most affected following mutation III cystic fibrosis transmembrane conductance regulator (CFTR) gene is
Correct Answer: Option C — Chloride
Detailed Academic Explanation:
Chloride is the correct answer to “The transport that will be the most affected following mutation III cystic fibrosis transmembrane conductance regulator (CFTR) gene is”. This question is standard in competitive examination syllabi for Cell Biology In Biotechnology.
💡Key Conceptual Anchor:Cell Biology In Biotechnology
Question 24 of 40
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Cholera toxin increases cAMP levels by
Correct Answer: Option B — Modifying Gs protein
Detailed Academic Explanation:
Modifying Gs protein is the correct answer to “Cholera toxin increases cAMP levels by”. This question is standard in competitive examination syllabi for Cell Biology In Biotechnology.
💡Key Conceptual Anchor:Cell Biology In Biotechnology
Question 25 of 40
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The genome is diploid at the end of which phases of a human mitotic cell cycle?
Correct Answer: Option B — G1 and M
Detailed Academic Explanation:
G1 and M is the correct answer to “The genome is diploid at the end of which phases of a human mitotic cell cycle”. This question is standard in competitive examination syllabi for Cell Biology In Biotechnology.
💡Key Conceptual Anchor:Cell Biology In Biotechnology
Question 26 of 40
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Match Group I with Group II . Group I Group II P. Fibronectin 1. Uptake of amino acids and glucose Q. Insulin 2. Trypsin inhibitor R. α-Macroglobulin 3. Binds iron S. Transferrin 4. Cell attachment to substratum
Correct Answer: Option D — P-4, Q-1, R-2, S-3
Detailed Academic Explanation:
P-4, Q-1, R-2, S-3 is the correct answer to “Match Group I with Group II . Group I Group II P. Fibronectin 1. Uptake of amino acids and glucose Q. Insulin 2. Trypsin inhibitor R. α-Macroglobulin 3. Binds iron S. Transferrin 4. Cell attachment to substratum”. This question is standard in competitive examination syllabi for Cell Biology In Biotechnology.
💡Key Conceptual Anchor:Cell Biology In Biotechnology
Question 27 of 40
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Gas vacuoles are present in
Correct Answer: Option A — Anabaena flos-aquae
Detailed Academic Explanation:
Anabaena flos-aquae is the correct answer to “Gas vacuoles are present in”. This question is standard in competitive examination syllabi for Cell Biology In Biotechnology.
💡Key Conceptual Anchor:Cell Biology In Biotechnology
Question 28 of 40
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At what stage mitosis occurs in bacteria?
Correct Answer: Option D — None of the above
Detailed Academic Explanation:
None of the above is the correct answer to “At what stage mitosis occurs in bacteria”. This question is standard in competitive examination syllabi for Cell Biology In Biotechnology.
💡Key Conceptual Anchor:Cell Biology In Biotechnology
Question 29 of 40
★ PPSC
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★ FPSC
In the cell cycle of a typical eukaryote, the sequence of events operating at the time of cell division is
Correct Answer: Option C — S phase → G2 phase → M phase → G1 phase
Detailed Academic Explanation:
S phase → G2 phase → M phase → G1 phase is the correct answer to “In the cell cycle of a typical eukaryote, the sequence of events operating at the time of cell division is”. This question is standard in competitive examination syllabi for Cell Biology In Biotechnology.
💡Key Conceptual Anchor:Cell Biology In Biotechnology
Question 30 of 40
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Match the proteins in Group I with cellular processes in Group II . List-I List-II P. p53 1. DNA packaging Q. Lysozyme 2. Apoptosis R. Tubulins 3. Hydrolysis of polysaccharides S. Histones 4. Chromosome segregation
Correct Answer: Option D — P-2, Q-3, R-4, S-1
Detailed Academic Explanation:
P-2, Q-3, R-4, S-1 is the correct answer to “Match the proteins in Group I with cellular processes in Group II . List-I List-II P. p53 1. DNA packaging Q. Lysozyme 2. Apoptosis R. Tubulins 3. Hydrolysis of polysaccharides S. Histones 4. Chromosome segregation”. This question is standard in competitive examination syllabi for Cell Biology In Biotechnology.
💡Key Conceptual Anchor:Cell Biology In Biotechnology
Question 31 of 40
★ PPSC
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A metacentric chromosomes will appear at anaphase as
Correct Answer: Option D — Y-shaped
Detailed Academic Explanation:
Y-shaped is the correct answer to “A metacentric chromosomes will appear at anaphase as”. This question is standard in competitive examination syllabi for Cell Biology In Biotechnology.
💡Key Conceptual Anchor:Cell Biology In Biotechnology
Question 32 of 40
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Histone proteins are synthesized in
Correct Answer: Option B — S-phase
Detailed Academic Explanation:
S-phase is the correct answer to “Histone proteins are synthesized in”. This question is standard in competitive examination syllabi for Cell Biology In Biotechnology.
💡Key Conceptual Anchor:Cell Biology In Biotechnology
Question 33 of 40
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Determine the correctness or otherwise of the following Assertion [A] and the Reason [R] regarding mammalian cells. Assertion [A]: Cells use Ca 2+ and not Na + , for cell to-cell signaling. Reason [R]: In the cytosol, concentration of Na + is lower than that of Ca 2+
Correct Answer: Option D — [A] is true but [R] is false
Detailed Academic Explanation:
[A] is true but [R] is false is the correct answer to “Determine the correctness or otherwise of the following Assertion [A] and the Reason [R] regarding mammalian cells. Assertion [A]: Cells use Ca 2+ and not Na + , for cell to-cell signaling. Reason [R]: In the cytosol, concentration of Na + is lower than that of Ca 2+”. This question is standard in competitive examination syllabi for Cell Biology In Biotechnology.
💡Key Conceptual Anchor:Cell Biology In Biotechnology
Question 34 of 40
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Smooth endoplasmic reticulum synthesizes
Correct Answer: Option C — Steroids and lipids
Detailed Academic Explanation:
Steroids and lipids is the correct answer to “Smooth endoplasmic reticulum synthesizes”. This question is standard in competitive examination syllabi for Cell Biology In Biotechnology.
💡Key Conceptual Anchor:Cell Biology In Biotechnology
Question 35 of 40
★ PPSC
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DNA synthesis in eukaryotes occurs during which phase of the mitotic cell cycle?
Correct Answer: Option C — S
Detailed Academic Explanation:
S is the correct answer to “DNA synthesis in eukaryotes occurs during which phase of the mitotic cell cycle”. This question is standard in competitive examination syllabi for Cell Biology In Biotechnology.
💡Key Conceptual Anchor:Cell Biology In Biotechnology
Question 36 of 40
★ PPSC
★ FPSC
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★ FPSC
Which one of the following statements regarding G proteins is incorrect?
Correct Answer: Option C — All G proteins are trimeric
Detailed Academic Explanation:
All G proteins are trimeric is the correct answer to “Which one of the following statements regarding G proteins is incorrect”. This question is standard in competitive examination syllabi for Cell Biology In Biotechnology.
💡Key Conceptual Anchor:Cell Biology In Biotechnology
Question 37 of 40
★ PPSC
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★ FPSC
If serum is removed from the growth medium of human embryonic kidney cell line (HEK), then the cells will
Correct Answer: Option C — Undergo cell cycle arrest
Detailed Academic Explanation:
Undergo cell cycle arrest is the correct answer to “If serum is removed from the growth medium of human embryonic kidney cell line (HEK), then the cells will”. This question is standard in competitive examination syllabi for Cell Biology In Biotechnology.
💡Key Conceptual Anchor:Cell Biology In Biotechnology
Question 38 of 40
★ PPSC
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Fusicoccin promotes cotyledon growth by promoting
Correct Answer: Option D — Cell wall acidification
Detailed Academic Explanation:
Cell wall acidification is the correct answer to “Fusicoccin promotes cotyledon growth by promoting”. This question is standard in competitive examination syllabi for Cell Biology In Biotechnology.
💡Key Conceptual Anchor:Cell Biology In Biotechnology
Question 39 of 40
★ PPSC
★ FPSC
★ PPSC
★ FPSC
In eukaryotic cell, DNA replication takes place during
Correct Answer: Option A — S-phase
Detailed Academic Explanation:
S-phase is the correct answer to “In eukaryotic cell, DNA replication takes place during”. This question is standard in competitive examination syllabi for Cell Biology In Biotechnology.
💡Key Conceptual Anchor:Cell Biology In Biotechnology
Question 40 of 40
★ PPSC
★ FPSC
★ PPSC
★ FPSC
Primary neutransmitter that playa role in sleep, appetite, arousal and mood is
Correct Answer: Option A — Serotonin
Detailed Academic Explanation:
Serotonin is the correct answer to “Primary neutransmitter that playa role in sleep, appetite, arousal and mood is”. This question is standard in competitive examination syllabi for Cell Biology In Biotechnology.
💡Key Conceptual Anchor:Cell Biology In Biotechnology
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Analytical Tools In Biotechnology — Part 1
Master the next curriculum module with 40 exam-standard MCQs.
💡Examiner's Advisory for Biotechnology Engineering
In competitive commission exams (FPSC, PPSC, KPPSC, SPSC, CSS, PMS), questions are frequently phrased with distractor options designed to catch rote learners. Whenever you answer an MCQ, read the Detailed Academic Explanation and Conceptual Anchor to understand why the remaining options are incorrect.