Immunology In Biotechnology — Part 1 MCQs with Explanations

Arginine is the correct answer to “Which one of the following amino acids is catalyzed by activated macrophages to produce reactive nitrogen species”. This question is standard in competitive examination syllabi for Immunology In Biotechnology.

Recombinant yeast expressing hepatitis B surface antigen is the correct answer to “Recombinant live attenuated vaccine against hepatitis B was prepared from”. This question is standard in competitive examination syllabi for Immunology In Biotechnology.

P and R only is the correct answer to “Which of the following statements about immune response are correct? P. T cells are activated by antigen-presenting cells. Q. Foreign peptides are not presented to helper T cells by class II MHC proteins. R. Dendritic cells are referred to as professional antigenpresenting cells.”. This question is standard in competitive examination syllabi for Immunology In Biotechnology.

C5b is the correct answer to “Which one of the following complement proteins is the initiator of the membrane attack complex”. This question is standard in competitive examination syllabi for Immunology In Biotechnology.

IgM is the correct answer to “Which class of antibody is first made by developing B cells inside bone marrow”. This question is standard in competitive examination syllabi for Immunology In Biotechnology.

CD4 + T cells is the correct answer to “Macrophages eliminate pathogenic bacteria upon activation by”. This question is standard in competitive examination syllabi for Immunology In Biotechnology.

P-3, Q-4, R-2, S-1 is the correct answer to “Match the items Group I with Group II . Group I Group II P. Programmed cell death at site of infection 1. TMV coat protein Q. Hormone upregulated during flooding stress 2. EPSP synthase R. Target for herbicide glyphosate 3. Hypersensitive response S. Pathogen-derived resistance 4. Ethylene”. This question is standard in competitive examination syllabi for Immunology In Biotechnology.

Variable region is the correct answer to “Idiotypic determinants of an antibody are associated with the”. This question is standard in competitive examination syllabi for Immunology In Biotechnology.

Virus infected cells is the correct answer to “Interferon β is produced by”. This question is standard in competitive examination syllabi for Immunology In Biotechnology.

The addition of N and P nucleotides is the correct answer to “Junctional diversity of antibody molecules results from”. This question is standard in competitive examination syllabi for Immunology In Biotechnology.

(A) is true but (R) is false is the correct answer to “Determine the correctness or otherwise of the following Assertion (A) and the Reason (R) . Assertion: IgM is found in serum as a pentameric protein consisting of five IgM monomers. Reason: The pentameric form of IgM is due to cross linking of IgM monomers via peptide bond.”. This question is standard in competitive examination syllabi for Immunology In Biotechnology.

Antibody is the correct answer to “Which one of the following is NOT a part of the human non-specific defense system”. This question is standard in competitive examination syllabi for Immunology In Biotechnology.

P-4, Q-1, R-2, S-3 is the correct answer to “Match the immunoglobulin class in Group I with its properties in Group II . Group I Group II P. IgG 1. Major antibody in external secretions such as bronchial mucus Q. IgA 2. Protects against parasites R. IgE 3. Antibody that appears first in serum after exposure to an antigen S. IgM 4. Antibody present in highest concentration in serum”. This question is standard in competitive examination syllabi for Immunology In Biotechnology.

From genome sequence to vaccine development is the correct answer to “Reverse vaccinology indicates”. This question is standard in competitive examination syllabi for Immunology In Biotechnology.

IFNα is the correct answer to “Viral replication within cells is inhibited by”. This question is standard in competitive examination syllabi for Immunology In Biotechnology.

Inter-chromosomal recombination is the correct answer to “Antibody diversity is generated by”. This question is standard in competitive examination syllabi for Immunology In Biotechnology.

P-3, Q-1, R-4, S-2 is the correct answer to “Match items in Group I with correct options from those given in Group II . Group I Group II P. Tissue plasminogen activator 1. Immunomodulator Q. Gamma interferon 2. Biodegradable plastic R. Podophyllotoxin 3. Clot dissolution S. Polyhydroxyalkanoate 4. Anti-tumor agent”. This question is standard in competitive examination syllabi for Immunology In Biotechnology.

Thick peptidoglycan layer prevents insertion of membrane attack complex into the inner membrane is the correct answer to “Gram-positive bacteria are generally resistant to complement-mediated lysis because”. This question is standard in competitive examination syllabi for Immunology In Biotechnology.

Immunodiffusion assay is the correct answer to “Reactions between antibodies and antigens that are detected by precipitate formation in an agar gel are referred as”. This question is standard in competitive examination syllabi for Immunology In Biotechnology.

IgG is the correct answer to “Based on the heavy chain, which one of the following antibodies has multiple subtypes”. This question is standard in competitive examination syllabi for Immunology In Biotechnology.

Prolong the persistence of antigen is the correct answer to “The role of an adjuvant is to”. This question is standard in competitive examination syllabi for Immunology In Biotechnology.

MHC I is the correct answer to “Endogenous antigens are presented on to the cell surface along with”. This question is standard in competitive examination syllabi for Immunology In Biotechnology.

Both (A) and (R) are false is the correct answer to “Determine the correctness or otherwise of the following Assertion (A) and Reason (R) . Assertion: An antigen recognized by one immunoglobulin subtype is not recognized by any other subtype. Reason: Immunoglobulin subtypes differ from each other both in the variable and in the constant regions.”. This question is standard in competitive examination syllabi for Immunology In Biotechnology.

Mice without thymus is the correct answer to “Nude mice refers to”. This question is standard in competitive examination syllabi for Immunology In Biotechnology.

P, Q and S only is the correct answer to “Which of the following statement(s) is/are CORRECT for antigen activated effector T cells? P. CD4+ cells make contact with macrophages and stimulate their microbicidal activity. Q. CD4+ cells make contact with B cells and stimulate them to differentiate into plasma cells. R. CD8+ cells make contact with B cells and stimulate them to differentiate into plasma cells. S. CD8+ cells make contact with virus infected cells and kill them.”. This question is standard in competitive examination syllabi for Immunology In Biotechnology.

Antigenic variation is the correct answer to “Which one of the following mechanisms is used by human pathogens to evade host immune responses”. This question is standard in competitive examination syllabi for Immunology In Biotechnology.

Have identical MHC haplotypes is the correct answer to “Dizygotic twins are connected to a single placenta during their embryonic development. These twins”. This question is standard in competitive examination syllabi for Immunology In Biotechnology.

Complement is the correct answer to “Heat inactivation of serum is done to inactivate”. This question is standard in competitive examination syllabi for Immunology In Biotechnology.

P-4, Q-2, R-3, S-6 is the correct answer to “Match the cells in Group I with their corresponding entries in Group II . Group I Group II P. Mast cells 1. Activation of the complement pathway Q. Natural killer cells 2. Expression of CD56 R. Neutrophils 3. Contains azurophilic granules S. Dendritic cells 4. Defense against helminthic infection 5. Production of antibodies specific to bacteria 6. Contains long membranous projections”. This question is standard in competitive examination syllabi for Immunology In Biotechnology.

Herceptin is the correct answer to “The first humanized monoclonal antibody approved for the treatment of breast cancer is”. This question is standard in competitive examination syllabi for Immunology In Biotechnology.

CDRs are from mouse, and the rest is from human is the correct answer to “A humanized antibody is one in which the”. This question is standard in competitive examination syllabi for Immunology In Biotechnology.

P-4, Q-2, R-1, S-3 is the correct answer to “Match the autoimmune diseases in Group I with the corresponding primarily affected organ in Group II . Group I Group II P. Hashimoto's disease 1. Brain Q. Juvenile diabetes 2. Pancreas R. Multiple sclerosis 3. Skeletal muscle S. Myasthenia gravis 4. Thyroid”. This question is standard in competitive examination syllabi for Immunology In Biotechnology.

In the class I MHC pathway, transporter associated antigen processing (TAP) protein is required for translocating processed peptides generated in the cytosol is the correct answer to “Which one of the following statements is true with regard to processing and presentation of protein antigens”. This question is standard in competitive examination syllabi for Immunology In Biotechnology.

P and Q only is the correct answer to “Which of the following cytokines are endogenous pyrogens? P. Tumor necrosis factor α Q. Interleukin 1 R. Transforming growth factor β S. Interleukin 10”. This question is standard in competitive examination syllabi for Immunology In Biotechnology.

Bone marrow is the correct answer to “B-lymphocytes originate from the bone marrow, whereas T lymphocytes originate from”. This question is standard in competitive examination syllabi for Immunology In Biotechnology.

P, Q is the correct answer to “Which of the following conditions promote the development of human autoimmune disorders? P. Inability to eliminate self-reactive lymphocytes Q. Generation of auto-antibodies R. Ability to eliminate self-reactive T cells S. Induction of regulatory T cells in the thymus”. This question is standard in competitive examination syllabi for Immunology In Biotechnology.

Memory B cells is the correct answer to “Which one of the following is not a principal component of innate immunity”. This question is standard in competitive examination syllabi for Immunology In Biotechnology.

Only primary response to the antigen is the correct answer to “A neonatally thymectomized mouse, immunized with protein antigen shows”. This question is standard in competitive examination syllabi for Immunology In Biotechnology.

Nude mice is the correct answer to “Which of these mice fall to develop a thymus”. This question is standard in competitive examination syllabi for Immunology In Biotechnology.

Antibodies that have catalytic activities is the correct answer to “Abzymes are”. This question is standard in competitive examination syllabi for Immunology In Biotechnology.